Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21
Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The liver is a key metabolic organ that controls whole-body physiology in response to nutrient availability. Mammalian target of rapamycin (mTOR) is a nutrient-activated kinase and central controller of growth and metabolism that is negatively regulated by the tumor suppressor tuberous sclerosis complex 1 (TSC1). To investigate the role of hepatic...
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Full title
Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21
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TN_cdi_proquest_journals_1554580136
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1554580136
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1412047111
