Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-s...
Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial
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Author / Creator
Garon, Edward B, Dr , Ciuleanu, Tudor-Eliade, Prof , Arrieta, Oscar, MD , Prabhash, Kumar, Prof , Syrigos, Konstantinos N, Prof , Goksel, Tuncay, Prof , Park, Keunchil, Prof , Gorbunova, Vera, MD , Kowalyszyn, Ruben Dario, MD , Pikiel, Joanna, MD , Czyzewicz, Grzegorz, MD , Orlov, Sergey V, Prof , Lewanski, Conrad R, MD , Thomas, Michael, Prof , Bidoli, Paolo, MD , Dakhil, Shaker, MD , Gans, Steven, MD , Kim, Joo-Hang, Prof , Grigorescu, Alexandru, Prof , Karaseva, Nina, MD , Reck, Martin, MD , Cappuzzo, Federico, MD , Alexandris, Ekaterine, MS , Sashegyi, Andreas, PhD , Yurasov, Sergey, MD and Pérol, Maurice, MD
Publisher
England: Elsevier Ltd
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English
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England: Elsevier Ltd
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Summary Background Ramucirumab is a human IgG1 monoclonal antibody that targets the extracellular domain of VEGFR-2. We aimed to assess efficacy and safety of treatment with docetaxel plus ramucirumab or placebo as second-line treatment for patients with stage IV non-small-cell-lung cancer (NSCLC) after platinum-based therapy. Methods In this multi...
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Full title
Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial
Authors, Artists and Contributors
Author / Creator
Ciuleanu, Tudor-Eliade, Prof
Arrieta, Oscar, MD
Prabhash, Kumar, Prof
Syrigos, Konstantinos N, Prof
Goksel, Tuncay, Prof
Park, Keunchil, Prof
Gorbunova, Vera, MD
Kowalyszyn, Ruben Dario, MD
Pikiel, Joanna, MD
Czyzewicz, Grzegorz, MD
Orlov, Sergey V, Prof
Lewanski, Conrad R, MD
Thomas, Michael, Prof
Bidoli, Paolo, MD
Dakhil, Shaker, MD
Gans, Steven, MD
Kim, Joo-Hang, Prof
Grigorescu, Alexandru, Prof
Karaseva, Nina, MD
Reck, Martin, MD
Cappuzzo, Federico, MD
Alexandris, Ekaterine, MS
Sashegyi, Andreas, PhD
Yurasov, Sergey, MD
Pérol, Maurice, MD
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TN_cdi_proquest_journals_1555409613
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1555409613
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ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(14)60845-X