Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells
Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Significance Diet-induced type 2 diabetes (T2D) is becoming a worldwide epidemic. Patients with T2D fail to respond to insulin normally and have elevated blood glucose and insulin. In autoimmune diabetes, blood glucose is elevated due to uncontrolled glucagon, a hormone normally suppressed and opposed by insulin. To study the role of glucagon in T2...
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Full title
Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells
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TN_cdi_proquest_journals_1564000231
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1564000231
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1409638111