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Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells

Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1564000231

Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells

About this item

Full title

Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (36), p.13217-13222

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Significance Diet-induced type 2 diabetes (T2D) is becoming a worldwide epidemic. Patients with T2D fail to respond to insulin normally and have elevated blood glucose and insulin. In autoimmune diabetes, blood glucose is elevated due to uncontrolled glucagon, a hormone normally suppressed and opposed by insulin. To study the role of glucagon in T2...

Alternative Titles

Full title

Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1564000231

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1564000231

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1409638111

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