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Taurolidine induces epithelial-mesenchymal transition via up-regulation of the transcription factor...

Taurolidine induces epithelial-mesenchymal transition via up-regulation of the transcription factor...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1611599031

Taurolidine induces epithelial-mesenchymal transition via up-regulation of the transcription factor Snail in human pancreatic cancer cell lines

About this item

Full title

Taurolidine induces epithelial-mesenchymal transition via up-regulation of the transcription factor Snail in human pancreatic cancer cell lines

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

International journal of colorectal disease, 2014-11, Vol.29 (11), p.1339-1348

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
The taurine derivative taurolidine (TRD) exerts anti-neoplastic effects in a variety of tumor models. On the other hand, TRD at low doses was shown to reduce cell-cell adhesion, a prerequisite for metastasis. The aim of this study was to elucidate the effects of low-dose TRD on pancreatic cancer.
Methods
Human pancreatic cancer cel...

Alternative Titles

Full title

Taurolidine induces epithelial-mesenchymal transition via up-regulation of the transcription factor Snail in human pancreatic cancer cell lines

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1611599031

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1611599031

Other Identifiers

ISSN

0179-1958

E-ISSN

1432-1262

DOI

10.1007/s00384-014-1998-4

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