Inflammatory caspases are innate immune receptors for intracellular LPS
Inflammatory caspases are innate immune receptors for intracellular LPS
About this item
Full title
Author / Creator
Shi, Jianjin , Zhao, Yue , Wang, Yupeng , Gao, Wenqing , Ding, Jingjin , Li, Peng , Hu, Liyan and Shao, Feng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The murine caspase-11 non-canonical inflammasome responds to various bacterial infections. Caspase-11 activation-induced pyroptosis, in response to cytoplasmic lipopolysaccharide (LPS), is critical for endotoxic shock in mice. The mechanism underlying cytosolic LPS sensing and the responsible pattern recognition receptor are unknown. Here we show t...
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Full title
Inflammatory caspases are innate immune receptors for intracellular LPS
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Record Identifier
TN_cdi_proquest_journals_1614047864
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1614047864
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13683
