Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hyp...
Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Activation of the transcription factor FoxO1 ameliorates vascular remodeling in pulmonary hypertension, pointing to a potential new therapeutic strategy for this disease.
Pulmonary hypertension (PH) is characterized by increased proliferation and apoptosis resistance of pulmonary artery smooth muscle cells (PASMCs). Forkhead box O (FoxO) transcr...
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Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension
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TN_cdi_proquest_journals_1621263488
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1621263488
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.3695
