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Oligomeric A[beta]-induced synaptic dysfunction in Alzheimer's disease

Oligomeric A[beta]-induced synaptic dysfunction in Alzheimer's disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1626757449

Oligomeric A[beta]-induced synaptic dysfunction in Alzheimer's disease

About this item

Full title

Oligomeric A[beta]-induced synaptic dysfunction in Alzheimer's disease

Publisher

London: BioMed Central Ltd

Journal title

Molecular neurodegeneration, 2014-11, Vol.9

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Alzheimer's disease (AD) is a devastating disease characterized by synaptic and neuronal loss in the elderly. Compelling evidence suggests that soluble amyloid-[beta] peptide (A[beta]) oligomers induce synaptic loss in AD. A[beta]-induced synaptic dysfunction is dependent on overstimulation of N-methyl-D-aspartate receptors (NMDARs) resulting in ab...

Alternative Titles

Full title

Oligomeric A[beta]-induced synaptic dysfunction in Alzheimer's disease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1626757449

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1626757449

Other Identifiers

ISSN

1750-1326

E-ISSN

1750-1326

DOI

10.1186/1750-1326-9-48

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