PDX1 in ducts is not required for postnatal formation of [beta]-Cells but is necessary for their sub...
PDX1 in ducts is not required for postnatal formation of [beta]-Cells but is necessary for their subsequent maturation.(ORIGINAL ARTICLE)
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Publisher
New York: American Diabetes Association
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Language
English
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New York: American Diabetes Association
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Contents
Pancreatic duodenal homeobox-1 (Pdx1), a transcription factor required for pancreatic development and maintenance of [beta]-cell function, was assessed for a possible role in postnatal [beta]-cell formation from progenitors in the pancreatic ducts by selectively deleting Pdx1 from the ducts. Carbonic anhydrase II [(CAII).sup.Cre]; [Pdx1.sup.Fl] mic...
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Full title
PDX1 in ducts is not required for postnatal formation of [beta]-Cells but is necessary for their subsequent maturation.(ORIGINAL ARTICLE)
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TN_cdi_proquest_journals_1628017908
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1628017908
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ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/db12-1833