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PDX1 in ducts is not required for postnatal formation of [beta]-Cells but is necessary for their sub...

PDX1 in ducts is not required for postnatal formation of [beta]-Cells but is necessary for their sub...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1628017908

PDX1 in ducts is not required for postnatal formation of [beta]-Cells but is necessary for their subsequent maturation.(ORIGINAL ARTICLE)

About this item

Full title

PDX1 in ducts is not required for postnatal formation of [beta]-Cells but is necessary for their subsequent maturation.(ORIGINAL ARTICLE)

Publisher

New York: American Diabetes Association

Journal title

Diabetes (New York, N.Y.), 2013-10, Vol.62 (10), p.3459

Language

English

Formats

Publication information

Publisher

New York: American Diabetes Association

More information

Scope and Contents

Contents

Pancreatic duodenal homeobox-1 (Pdx1), a transcription factor required for pancreatic development and maintenance of [beta]-cell function, was assessed for a possible role in postnatal [beta]-cell formation from progenitors in the pancreatic ducts by selectively deleting Pdx1 from the ducts. Carbonic anhydrase II [(CAII).sup.Cre]; [Pdx1.sup.Fl] mic...

Alternative Titles

Full title

PDX1 in ducts is not required for postnatal formation of [beta]-Cells but is necessary for their subsequent maturation.(ORIGINAL ARTICLE)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1628017908

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1628017908

Other Identifiers

ISSN

0012-1797

E-ISSN

1939-327X

DOI

10.2337/db12-1833

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