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PPAR[alpha] and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of...

PPAR[alpha] and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1628897400

PPAR[alpha] and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of white adipocytes to protect against obesity and metabolic disorders

About this item

Full title

PPAR[alpha] and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of white adipocytes to protect against obesity and metabolic disorders

Publisher

New York: American Diabetes Association

Journal title

Diabetes (New York, N.Y.), 2013-12, Vol.62 (12), p.4122

Language

English

Formats

Publication information

Publisher

New York: American Diabetes Association

More information

Scope and Contents

Contents

Erythropoietin (EPO) has shown beneficial effects in the regulation of obesity and metabolic syndrome; however, the detailed mechanism is still largely unknown. Here, we created mice with adipocyte-specific deletion of EPO receptor. These mice exhibited obesity and decreased glucose tolerance and insulin sensitivity, especially when fed a high-fat...

Alternative Titles

Full title

PPAR[alpha] and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of white adipocytes to protect against obesity and metabolic disorders

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1628897400

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1628897400

Other Identifiers

ISSN

0012-1797

E-ISSN

1939-327X

DOI

10.2337/db13-0518

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