PPAR[alpha] and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of...
PPAR[alpha] and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of white adipocytes to protect against obesity and metabolic disorders
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Publisher
New York: American Diabetes Association
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Language
English
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Publisher
New York: American Diabetes Association
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Contents
Erythropoietin (EPO) has shown beneficial effects in the regulation of obesity and metabolic syndrome; however, the detailed mechanism is still largely unknown. Here, we created mice with adipocyte-specific deletion of EPO receptor. These mice exhibited obesity and decreased glucose tolerance and insulin sensitivity, especially when fed a high-fat...
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Full title
PPAR[alpha] and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of white adipocytes to protect against obesity and metabolic disorders
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TN_cdi_proquest_journals_1628897400
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1628897400
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ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/db13-0518