Mapping of long-range INS promoter interactions reveals a role for calcium-activated chloride channe...
Mapping of long-range INS promoter interactions reveals a role for calcium-activated chloride channel ANO1 in insulin secretion
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Significance Within the cell nucleus, the genetic material is organized into loop domains that transiently bring together genes separated by various distances along linear DNA. We asked whether the insulin ( INS ) gene in human pancreatic beta cells, which secrete the insulin protein, makes contact with other genes that play some role in insulin fu...
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Full title
Mapping of long-range INS promoter interactions reveals a role for calcium-activated chloride channel ANO1 in insulin secretion
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TN_cdi_proquest_journals_1628903921
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1628903921
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1419240111
