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Overcoming the limitations of directed C–H functionalizations of heterocycles

Overcoming the limitations of directed C–H functionalizations of heterocycles

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1629594633

Overcoming the limitations of directed C–H functionalizations of heterocycles

About this item

Full title

Overcoming the limitations of directed C–H functionalizations of heterocycles

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2014-11, Vol.515 (7527), p.389-393

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A robust and synthetically useful method is reported that overcomes the complications associated with performing C–H functionalization reactions on heterocycles; a reactive PdX
2
(X = ArCONOMe) species is generated
in situ
, and is directed to the appropriate C–H bond by an
N
-methoxy amide group.
Heterocycle poisoning bypassed...

Alternative Titles

Full title

Overcoming the limitations of directed C–H functionalizations of heterocycles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1629594633

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1629594633

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature13885

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