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Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1634873847

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

About this item

Full title

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (48), p.17128-17133

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Significance Serogroup B meningococcus (MenB) causes severe sepsis and invasive meningococcal disease, particularly affecting young children and adolescents. The genome-derived vaccine 4CMenB that targets MenB, has now been approved in over 30 countries worldwide. Here we report the crystal structure of the trimeric autotransporter Neisserial adhes...

Alternative Titles

Full title

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1634873847

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1634873847

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1419686111

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