Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain
Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain
About this item
Full title
Author / Creator
Xu, Chao , Wang, Xiao , Liu, Ke , Roundtree, Ian A , Tempel, Wolfram , Li, Yanjun , Lu, Zhike , He, Chuan and Min, Jinrong
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
N
6
-methyladenosine (m
6
A) is an abundant eukaryotic RNA modification that regulates mRNA stability. Biochemical analysis and crystallographic visualization of m
6
A-YTHDC1 interactions establish this YTH family member as an m
6
A reader and explain its RNA consensus sequence selectivity.
N
6
-methyladenosine (m
Alternative Titles
Full title
Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_journals_1647085275
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1647085275
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.1654
