Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor...
Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Nancy Jenkins and colleagues report the use of
Sleeping Beauty
transposon mutagenesis screens in mice to identify new genes involved in tumor progression in colorectal cancer. They identify 111 common transposon insertion sites present in all cohorts, including
Znf292
, a new tumor suppressor whose human counterpart is also mutated in h...
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Full title
Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression
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TN_cdi_proquest_journals_1654942899
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1654942899
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3175