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Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor...

Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1654942899

Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression

About this item

Full title

Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2015-02, Vol.47 (2), p.142-150

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Nancy Jenkins and colleagues report the use of
Sleeping Beauty
transposon mutagenesis screens in mice to identify new genes involved in tumor progression in colorectal cancer. They identify 111 common transposon insertion sites present in all cohorts, including
Znf292
, a new tumor suppressor whose human counterpart is also mutated in h...

Alternative Titles

Full title

Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1654942899

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1654942899

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.3175

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