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Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots a...

Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1654943486

Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism

About this item

Full title

Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2015-02, Vol.47 (2), p.158-163

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Ding Ma, Hui Wang, Xun Xu and colleagues report a genome-wide map of HPV integration sites in cervical cancer samples and cell lines. In addition to discovering new integration hot spots, the authors identify microhomology-mediated DNA repair as a likely mechanism by which HPV integrates into the human genome.
Human papillomavirus (HPV) integrat...

Alternative Titles

Full title

Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1654943486

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1654943486

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.3178

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