Indomethacin suppresses LAMP-2 expression and induces lipophagy and lipoapoptosis in rat enterocytes...
Indomethacin suppresses LAMP-2 expression and induces lipophagy and lipoapoptosis in rat enterocytes via the ER stress pathway
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Publisher
Tokyo: Springer Japan
Journal title
Language
English
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Publisher
Tokyo: Springer Japan
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Contents
Background
Indomethacin enhances small intestinal epithelial cell apoptosis, which may account for mucosal ulceration. However, the involvement of autophagy in indomethacin-induced enterocyte damage is unreported.
Methods
Using light microscopy and electron microscopy techniques, Western blot analysis, and pharmacological inhibition of aut...
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Full title
Indomethacin suppresses LAMP-2 expression and induces lipophagy and lipoapoptosis in rat enterocytes via the ER stress pathway
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Record Identifier
TN_cdi_proquest_journals_1679015755
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1679015755
Other Identifiers
ISSN
0944-1174
E-ISSN
1435-5922
DOI
10.1007/s00535-014-0995-2
