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The influences of CYP2D6 genotypes and drug interactions on the pharmacokinetics of venlafaxine: exp...

The influences of CYP2D6 genotypes and drug interactions on the pharmacokinetics of venlafaxine: exp...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1679665403

The influences of CYP2D6 genotypes and drug interactions on the pharmacokinetics of venlafaxine: exploring predictive biomarkers for treatment outcomes

About this item

Full title

The influences of CYP2D6 genotypes and drug interactions on the pharmacokinetics of venlafaxine: exploring predictive biomarkers for treatment outcomes

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Psychopharmacology, 2015-06, Vol.232 (11), p.1899-1909

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Rationale
Two biomarkers: concentration ratio of
O
-desmethylvenlafaxine/venlafaxine and concentration sum of venlafaxine + 
O
-desmethylvenlafaxine were adopted to indicate venlafaxine responses, but neither is validated.
Objectives
To evaluate the ability of two biomarkers in reflecting venlafaxine pharmacokinetic variations,...

Alternative Titles

Full title

The influences of CYP2D6 genotypes and drug interactions on the pharmacokinetics of venlafaxine: exploring predictive biomarkers for treatment outcomes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1679665403

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1679665403

Other Identifiers

ISSN

0033-3158

E-ISSN

1432-2072

DOI

10.1007/s00213-014-3825-6

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