CYP2D44 polymorphisms in cynomolgus and rhesus macaques
CYP2D44 polymorphisms in cynomolgus and rhesus macaques
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Publisher
Dordrecht: Springer Netherlands
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Language
English
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Publisher
Dordrecht: Springer Netherlands
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Contents
Macaques, including cynomolgus and rhesus macaques, are important animal species used in drug metabolism studies. CYP2D44 is expressed in cynomolgus macaque liver and encodes a functional drug metabolizing enzyme, metabolizing typical human CYP2D substrates such as bufuralol and dextromethorphan. CYP2D44 is highly homologous to human CYP2D6 that is...
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Full title
CYP2D44 polymorphisms in cynomolgus and rhesus macaques
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TN_cdi_proquest_journals_1686748402
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1686748402
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ISSN
0301-4851
E-ISSN
1573-4978
DOI
10.1007/s11033-015-3863-0
