Regulation of endoplasmic reticulum turnover by selective autophagy
Regulation of endoplasmic reticulum turnover by selective autophagy
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Author / Creator
Khaminets, Aliaksandr , Heinrich, Theresa , Mari, Muriel , Grumati, Paolo , Huebner, Antje K. , Akutsu, Masato , Liebmann, Lutz , Stolz, Alexandra , Nietzsche, Sandor , Koch, Nicole , Mauthe, Mario , Katona, Istvan , Qualmann, Britta , Weis, Joachim , Reggiori, Fulvio , Kurth, Ingo , Hübner, Christian A. and Dikic, Ivan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The protein FAM134B is an endoplasmic reticulum (ER)-resident receptor that facilitates ER autophagy, and downregulation of this protein (mutations of which are also known to cause sensory neuropathy in humans) results in expanded ER structures and degeneration of mouse sensory neurons.
ER-phagy receptors mapped
The endoplasmic reticulum (ER)...
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Full title
Regulation of endoplasmic reticulum turnover by selective autophagy
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TN_cdi_proquest_journals_1690371902
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1690371902
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature14498
