Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicist...
Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: two randomised, double-blind, phase 3, non-inferiority trials
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Sax, Paul E, Dr Prof , Wohl, David, MD , Yin, Michael T, Prof , Post, Frank, MD , DeJesus, Edwin, MD , Saag, Michael, MD , Pozniak, Anton, MD , Thompson, Melanie, MD , Podzamczer, Daniel, MD , Molina, Jean Michel, Prof , Oka, Shinichi, MD , Koenig, Ellen, MD , Trottier, Benoit, MD , Andrade-Villanueva, Jaime, MD , Crofoot, Gordon, MD , Custodio, Joseph M, PharmD , Plummer, Andrew, MS , Zhong, Lijie, PhD , Cao, Huyen, MD , Martin, Hal, MD , Callebaut, Christian, PhD , Cheng, Andrew K, MD , Fordyce, Marshall W, MD , McCallister, Scott, MD and GS-US-292-0104/0111 Study Team
Publisher
England: Elsevier Ltd
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English
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Publisher
England: Elsevier Ltd
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Contents
Summary Background Tenofovir disoproxil fumarate can cause renal and bone toxic effects related to high plasma tenofovir concentrations. Tenofovir alafenamide is a novel tenofovir prodrug with a 90% reduction in plasma tenofovir concentrations. Tenofovir alafenamide-containing regimens can have improved renal and bone safety compared with tenofovir...
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Full title
Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: two randomised, double-blind, phase 3, non-inferiority trials
Authors, Artists and Contributors
Author / Creator
Wohl, David, MD
Yin, Michael T, Prof
Post, Frank, MD
DeJesus, Edwin, MD
Saag, Michael, MD
Pozniak, Anton, MD
Thompson, Melanie, MD
Podzamczer, Daniel, MD
Molina, Jean Michel, Prof
Oka, Shinichi, MD
Koenig, Ellen, MD
Trottier, Benoit, MD
Andrade-Villanueva, Jaime, MD
Crofoot, Gordon, MD
Custodio, Joseph M, PharmD
Plummer, Andrew, MS
Zhong, Lijie, PhD
Cao, Huyen, MD
Martin, Hal, MD
Callebaut, Christian, PhD
Cheng, Andrew K, MD
Fordyce, Marshall W, MD
McCallister, Scott, MD
GS-US-292-0104/0111 Study Team
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TN_cdi_proquest_journals_1691310963
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1691310963
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(15)60616-X