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Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicist...

Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicist...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1691310963

Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: two randomised, double-blind, phase 3, non-inferiority trials

About this item

Full title

Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: two randomised, double-blind, phase 3, non-inferiority trials

Publisher

England: Elsevier Ltd

Journal title

The Lancet (British edition), 2015-06, Vol.385 (9987), p.2606-2615

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

More information

Scope and Contents

Contents

Summary Background Tenofovir disoproxil fumarate can cause renal and bone toxic effects related to high plasma tenofovir concentrations. Tenofovir alafenamide is a novel tenofovir prodrug with a 90% reduction in plasma tenofovir concentrations. Tenofovir alafenamide-containing regimens can have improved renal and bone safety compared with tenofovir...

Alternative Titles

Full title

Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: two randomised, double-blind, phase 3, non-inferiority trials

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1691310963

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1691310963

Other Identifiers

ISSN

0140-6736

E-ISSN

1474-547X

DOI

10.1016/S0140-6736(15)60616-X

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