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Impact of the CYP3A4 metabolic activity and CYP2C19 Polymorphisms on Antiplatelet effects of clopido...

Impact of the CYP3A4 metabolic activity and CYP2C19 Polymorphisms on Antiplatelet effects of clopido...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1693851549

Impact of the CYP3A4 metabolic activity and CYP2C19 Polymorphisms on Antiplatelet effects of clopidogrel in Russian Patients with acute Coronary Syndrome undergoing coronary stent implantation

About this item

Full title

Impact of the CYP3A4 metabolic activity and CYP2C19 Polymorphisms on Antiplatelet effects of clopidogrel in Russian Patients with acute Coronary Syndrome undergoing coronary stent implantation

Publisher

Bridgewater: Elsevier Inc

Journal title

Clinical therapeutics, 2015-08, Vol.37 (8), p.e78-e79

Language

English

Formats

Publication information

Publisher

Bridgewater: Elsevier Inc

More information

Scope and Contents

Contents

Material and Methods We determined the CYP2C19 genotypes (Real-time PCR) and CYP3A4 metabolic activity (6b-hydroxycortisol/cortisol (6-OHC/FC) in urine were determined by high-performance liquid chromatography) of 81 subjects with acute coronary syndromes (ACS) undergoing coronary stent implantation (62 male patients, mean age 64 years) receiving c...

Alternative Titles

Full title

Impact of the CYP3A4 metabolic activity and CYP2C19 Polymorphisms on Antiplatelet effects of clopidogrel in Russian Patients with acute Coronary Syndrome undergoing coronary stent implantation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1693851549

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1693851549

Other Identifiers

ISSN

0149-2918

E-ISSN

1879-114X

DOI

10.1016/j.clinthera.2015.05.226

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