ITI-007 demonstrates brain occupancy at serotonin 5-HT^sub 2A^ and dopamine D^sub 2^ receptors and s...
ITI-007 demonstrates brain occupancy at serotonin 5-HT^sub 2A^ and dopamine D^sub 2^ receptors and serotonin transporters using positron emission tomography in healthy volunteers
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Publisher
Heidelberg: Springer Nature B.V
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Language
English
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Publisher
Heidelberg: Springer Nature B.V
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Contents
Central modulation of serotonin and dopamine underlies efficacy for a variety of psychiatric therapeutics. ITI-007 is an investigational new drug in development for treatment of schizophrenia, mood disorders, and other neuropsychiatric disorders. The purpose of this study was to determine brain occupancy of ITI-007 at serotonin 5-HT^sub 2A^ recepto...
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Full title
ITI-007 demonstrates brain occupancy at serotonin 5-HT^sub 2A^ and dopamine D^sub 2^ receptors and serotonin transporters using positron emission tomography in healthy volunteers
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TN_cdi_proquest_journals_1696150398
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1696150398
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ISSN
0033-3158
E-ISSN
1432-2072
DOI
10.1007/s00213-015-3922-1
