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Microbiota regulates type 1 diabetes through Toll-like receptors

Microbiota regulates type 1 diabetes through Toll-like receptors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1704124252

Microbiota regulates type 1 diabetes through Toll-like receptors

About this item

Full title

Microbiota regulates type 1 diabetes through Toll-like receptors

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (32), p.9973-9977

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Deletion of the innate immune adaptor myeloid differentiation primary response gene 88 (MyD88) in the nonobese diabetic (NOD) mouse model of type 1 diabetes (T1D) results in microbiota-dependent protection from the disease: MyD88-negative mice in germfree (GF), but not in specific pathogen-free conditions develop the disease. These results could be...

Alternative Titles

Full title

Microbiota regulates type 1 diabetes through Toll-like receptors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1704124252

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1704124252

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1508740112

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