Log in to save to my catalogue

A common glycan structure on immunoglobulin G for enhancement of effector functions

A common glycan structure on immunoglobulin G for enhancement of effector functions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1708614653

A common glycan structure on immunoglobulin G for enhancement of effector functions

About this item

Full title

A common glycan structure on immunoglobulin G for enhancement of effector functions

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (34), p.10611-10616

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Antibodies have been developed as therapeutic agents for the treatment of cancer, infection, and inflammation. In addition to binding activity toward the target, antibodies also exhibit effector-mediated activities through the interaction of the Fc glycan and the Fc receptors on immune cells. To identify the optimal glycan structures for individual...

Alternative Titles

Full title

A common glycan structure on immunoglobulin G for enhancement of effector functions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1708614653

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1708614653

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1513456112

How to access this item