Artesunate Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Suppressing TLR4, M...
Artesunate Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Suppressing TLR4, MyD88 Expression, and NF-[kappa]B Activation in Microglial Cells
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Author / Creator
Wang, Dunjing , Shi, Jun , Lv, Shuiqing , Xu, Weiwei , Li, Jizhen , Ge, Wei , Xiao, Chenghua , Geng, Deqin and Liu, Yonghai
Publisher
New York: Springer Nature B.V
Journal title
Language
English
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Publication information
Publisher
New York: Springer Nature B.V
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Contents
Microglia are considered as a major target in the prevention of neuroinflammation by modulating the production of pro-inflammatory mediators. Artesunate, a water-soluble artemisinin derivative, exerts an anti-inflammatory effect. In the present study, we showed artesunate dose-dependently suppressed the lipopolysaccharide (LPS)-induced production o...
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Full title
Artesunate Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Suppressing TLR4, MyD88 Expression, and NF-[kappa]B Activation in Microglial Cells
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Record Identifier
TN_cdi_proquest_journals_1709515510
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1709515510
Other Identifiers
ISSN
0360-3997
E-ISSN
1573-2576
DOI
10.1007/s10753-015-0172-7
