Log in to save to my catalogue

Histamine H^sub 1^ receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine...

Histamine H^sub 1^ receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1709594916

Histamine H^sub 1^ receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers

About this item

Full title

Histamine H^sub 1^ receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers

Publisher

Heidelberg: Springer Nature B.V

Journal title

Psychopharmacology, 2015-10, Vol.232 (19), p.3497

Language

English

Formats

Publication information

Publisher

Heidelberg: Springer Nature B.V

More information

Scope and Contents

Contents

Rationale Histamine H^sub 1^ antagonists have hypnotic, appetite-promoting, and sedative side effects. Most second-generation antipsychotics have potent antagonistic effects on histamine H^sub 1^ receptor (H1R). Positron emission tomography (PET) can measure the H1R occupancy (H1RO) in vivo, although there are no reports regarding antipsychotics. O...

Alternative Titles

Full title

Histamine H^sub 1^ receptor occupancy by the new-generation antipsychotics olanzapine and quetiapine: a positron emission tomography study in healthy volunteers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1709594916

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1709594916

Other Identifiers

ISSN

0033-3158

E-ISSN

1432-2072

DOI

10.1007/s00213-015-4002-2

How to access this item