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Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component

Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1713645835

Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component

About this item

Full title

Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2015-09, Vol.373 (12), p.1106-1114

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

A two-step process, in which circulating levels of amyloid P are reduced and then anti–serum amyloid P antibody is given to activate macrophage clearance mechanisms of tissue deposits, appears to reduce amyloid deposits in liver and some other organs.
In systemic amyloidosis, the extracellular deposition of normally soluble plasma proteins as in...

Alternative Titles

Full title

Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1713645835

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1713645835

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1504942

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