Paraxanthine/Caffeine Concentration Ratios in Hair: An Alternative for Plasma-Based Phenotyping of C...
Paraxanthine/Caffeine Concentration Ratios in Hair: An Alternative for Plasma-Based Phenotyping of Cytochrome P450 1A2?
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Cham: Springer International Publishing
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English
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Cham: Springer International Publishing
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Background and Objective
Although metabolite-to-parent drug concentration ratios in hair have been suggested as a possible tool to study the metabolism of drugs in a non-invasive way, no studies are available that evaluated this in a systematic way. Cytochrome P450 (CYP) 1A2 is a drug-metabolizing enzyme characterized by large inter-individual d...
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Paraxanthine/Caffeine Concentration Ratios in Hair: An Alternative for Plasma-Based Phenotyping of Cytochrome P450 1A2?
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TN_cdi_proquest_journals_1716013682
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1716013682
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ISSN
0312-5963
E-ISSN
1179-1926
DOI
10.1007/s40262-015-0237-7