A new therapeutic effect of simvastatin revealed by functional improvement in muscular dystrophy
A new therapeutic effect of simvastatin revealed by functional improvement in muscular dystrophy
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Duchenne muscular dystrophy (DMD) is a lethal, degenerative muscle disease with no effective treatment. DMD muscle pathogenesis is characterized by chronic inflammation, oxidative stress, and fibrosis. Statins, cholesterol-lowering drugs, inhibit these deleterious processes in ischemic diseases affecting skeletal muscle, and therefore have potentia...
Alternative Titles
Full title
A new therapeutic effect of simvastatin revealed by functional improvement in muscular dystrophy
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TN_cdi_proquest_journals_1726484374
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1726484374
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1509536112
