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Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-[gamma]

Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-[gamma]

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1731819109

Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-[gamma]

About this item

Full title

Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-[gamma]

Publisher

London: Elsevier Limited

Journal title

Journal of investigative dermatology, 2015-11, Vol.135 (11), p.2775

Language

English

Formats

Publication information

Publisher

London: Elsevier Limited

More information

Scope and Contents

Contents

Melanoma is believed to be a highly immunogenic tumor and recent developments in immunotherapies are promising. IFN-γ produced by immune cells has a crucial role in tumor immune surveillance; however, it has also been reported to be pro-tumorigenic. In the current study, we found that IFN-γ enhances the expression of CD74, which interacts with its...

Alternative Titles

Full title

Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-[gamma]

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1731819109

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1731819109

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1038/jid.2015.204

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