Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-[gamma]
Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-[gamma]
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London: Elsevier Limited
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Language
English
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Publisher
London: Elsevier Limited
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Contents
Melanoma is believed to be a highly immunogenic tumor and recent developments in immunotherapies are promising. IFN-γ produced by immune cells has a crucial role in tumor immune surveillance; however, it has also been reported to be pro-tumorigenic. In the current study, we found that IFN-γ enhances the expression of CD74, which interacts with its...
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Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-[gamma]
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TN_cdi_proquest_journals_1731819109
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1731819109
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ISSN
0022-202X
E-ISSN
1523-1747
DOI
10.1038/jid.2015.204