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Maternal CD4⁺ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman...

Maternal CD4⁺ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1732845918

Maternal CD4⁺ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission

About this item

Full title

Maternal CD4⁺ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (44), p.13645-13650

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Elucidation of maternal immune correlates of protection against congenital cytomegalovirus (CMV) is necessary to inform future vaccine design. Here, we present a novel rhesus macaque model of placental rhesus CMV (rhCMV) transmission and use it to dissect determinants of protection against congenital transmission following primary maternal rhCMV in...

Alternative Titles

Full title

Maternal CD4⁺ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1732845918

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1732845918

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1511526112

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