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Signal integration by Ca^sup 2+^ regulates intestinal stem-cell activity

Signal integration by Ca^sup 2+^ regulates intestinal stem-cell activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1749281673

Signal integration by Ca^sup 2+^ regulates intestinal stem-cell activity

About this item

Full title

Signal integration by Ca^sup 2+^ regulates intestinal stem-cell activity

Publisher

London: Nature Publishing Group

Journal title

Nature (London), 2015-12, Vol.528 (7581), p.212

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group

More information

Scope and Contents

Contents

Somatic stem cells maintain tissue homeostasis by dynamically adjusting proliferation and differentiation in response to stress and metabolic cues. Here we identify Ca^sup 2+^ signalling as a central regulator of intestinal stem cell (ISC) activity in Drosophila. We show that dietary l-glutamate stimulates ISC division and gut growth. The metabotro...

Alternative Titles

Full title

Signal integration by Ca^sup 2+^ regulates intestinal stem-cell activity

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1749281673

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1749281673

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature16170

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