Bio-generation of stable isotope-labeled internal standards for absolute and relative quantitation o...
Bio-generation of stable isotope-labeled internal standards for absolute and relative quantitation of phase II drug metabolites in plasma samples using LC–MS/MS
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
Quantification of drug metabolites in biological samples has been of great interest in current pharmaceutical research, since metabolite concentrations and pharmacokinetics can contribute to a better understanding of the toxicity of drug candidates. Two major categories of Phase II metabolites, glucuronide conjugates and glutathione conjugates, may...
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Full title
Bio-generation of stable isotope-labeled internal standards for absolute and relative quantitation of phase II drug metabolites in plasma samples using LC–MS/MS
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TN_cdi_proquest_journals_1754634848
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1754634848
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ISSN
1618-2642
E-ISSN
1618-2650
DOI
10.1007/s00216-015-8614-5
