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Cellular volume regulation by anoctamin 6: Ca^sup 2+^, phospholipase A2 and osmosensing

Cellular volume regulation by anoctamin 6: Ca^sup 2+^, phospholipase A2 and osmosensing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1756903890

Cellular volume regulation by anoctamin 6: Ca^sup 2+^, phospholipase A2 and osmosensing

About this item

Full title

Cellular volume regulation by anoctamin 6: Ca^sup 2+^, phospholipase A2 and osmosensing

Publisher

Heidelberg: Springer Nature B.V

Journal title

Pflügers Archiv, 2016-02, Vol.468 (2), p.335

Language

English

Formats

Publication information

Publisher

Heidelberg: Springer Nature B.V

More information

Scope and Contents

Contents

During cell swelling, Cl^sup -^ channels are activated to lower intracellular Cl^sup -^ concentrations and to reduce cell volume, a process termed regulatory volume decrease (RVD). We show that anoctamin 6 (ANO6; TMEM16F) produces volume-regulated anion currents and controls cell volume in four unrelated cell types. Volume regulation is compromised...

Alternative Titles

Full title

Cellular volume regulation by anoctamin 6: Ca^sup 2+^, phospholipase A2 and osmosensing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1756903890

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1756903890

Other Identifiers

ISSN

0031-6768

E-ISSN

1432-2013

DOI

10.1007/s00424-015-1739-8

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