Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification
Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Filamentation induced by cyclic AMP (FIC)-domain enzymes catalyze adenylylation or other posttranslational modifications of target proteins to control their function. Recently, we have shown that Fic enzymes are autoinhibited by an α-helix (αinh) that partly obstructs the active site. For the single-domain class III Fic proteins, the αinh is locate...
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Full title
Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification
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TN_cdi_proquest_journals_1765606479
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1765606479
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1516930113
