The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
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United States: American Association for the Advancement of Science
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Language
English
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United States: American Association for the Advancement of Science
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Viral infection during pregnancy has been correlated with increased frequency of autism spectrum disorder (ASD) in offspring. This observation has been modeled in rodents subjected to maternal immune activation (MIA). The immune cell populations critical in the MIA model have not been identified. Using both genetic mutants and blocking antibodies i...
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Full title
The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
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TN_cdi_proquest_journals_1768233373
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1768233373
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aad0314
