EGFR participates downstream of ER[alpha] in estradiol-17[beta]-d-glucuronide-induced impairment of...
EGFR participates downstream of ER[alpha] in estradiol-17[beta]-d-glucuronide-induced impairment of Abcc2 function in isolated rat hepatocyte couplets
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Heidelberg: Springer Nature B.V
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English
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Heidelberg: Springer Nature B.V
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Estradiol-17[beta]-d-glucuronide (E17G) induces acute endocytic internalization of canalicular transporters, including multidrug resistance-associated protein 2 (Abcc2) in rat, generating cholestasis. Several proteins organized in at least two different signaling pathways are involved in E17G cholestasis: one pathway involves estrogen receptor alph...
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EGFR participates downstream of ER[alpha] in estradiol-17[beta]-d-glucuronide-induced impairment of Abcc2 function in isolated rat hepatocyte couplets
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TN_cdi_proquest_journals_1771778809
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1771778809
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0340-5761
E-ISSN
1432-0738
DOI
10.1007/s00204-015-1507-8