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ObRb downregulation increases breast cancer cell sensitivity to tamoxifen

ObRb downregulation increases breast cancer cell sensitivity to tamoxifen

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1774963470

ObRb downregulation increases breast cancer cell sensitivity to tamoxifen

About this item

Full title

ObRb downregulation increases breast cancer cell sensitivity to tamoxifen

Publisher

Dordrecht: Springer Netherlands

Journal title

Tumor biology, 2015-09, Vol.36 (9), p.6813-6821

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

More information

Scope and Contents

Contents

Leptin is a potent adipokine that plays an important role in the progression of breast cancer and interferes with the action of tamoxifen. We investigated the molecular mechanism underlying the effect of leptin on tamoxifen resistance in breast cancer cells that express leptin receptor (ObRb), and evaluated the impact of ObRb suppression on tamoxif...

Alternative Titles

Full title

ObRb downregulation increases breast cancer cell sensitivity to tamoxifen

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1774963470

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1774963470

Other Identifiers

ISSN

1010-4283

E-ISSN

1423-0380

DOI

10.1007/s13277-015-3375-5

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