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THU0038 Activation of Inflammasome in the Salivary Gland Epithelial Cells of SjÖGren's Syndrome Pati...

THU0038 Activation of Inflammasome in the Salivary Gland Epithelial Cells of SjÖGren's Syndrome Pati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1777975505

THU0038 Activation of Inflammasome in the Salivary Gland Epithelial Cells of SjÖGren's Syndrome Patients Imposed by Aberrant Dnase1 Expression and Extracellular DNA Accumulation

About this item

Full title

THU0038 Activation of Inflammasome in the Salivary Gland Epithelial Cells of SjÖGren's Syndrome Patients Imposed by Aberrant Dnase1 Expression and Extracellular DNA Accumulation

Publisher

Kidlington: Elsevier Limited

Journal title

Annals of the rheumatic diseases, 2014-06, Vol.73 (Suppl 2), p.189-190

Language

English

Formats

Publication information

Publisher

Kidlington: Elsevier Limited

More information

Scope and Contents

Contents

Background Evidence from this laboratory had indicated that the epithelia of primary Sjögren's syndrome (SS) patients, by virtue of an intrinsically activated cell status, may have a crucial pathogenetic role in this disorder. The degradation of necrotic cell debris by exonucleases, such as DNase1, is thought protective against the inflammagenic ac...

Alternative Titles

Full title

THU0038 Activation of Inflammasome in the Salivary Gland Epithelial Cells of SjÖGren's Syndrome Patients Imposed by Aberrant Dnase1 Expression and Extracellular DNA Accumulation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1777975505

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1777975505

Other Identifiers

ISSN

0003-4967

E-ISSN

1468-2060

DOI

10.1136/annrheumdis-2014-eular.5771

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