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PP2A methylation controls sensitivity and resistance to [Beta]-amyloid-induced cognitive and electro...

PP2A methylation controls sensitivity and resistance to [Beta]-amyloid-induced cognitive and electro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1780547567

PP2A methylation controls sensitivity and resistance to [Beta]-amyloid-induced cognitive and electrophysiological impairments

About this item

Full title

PP2A methylation controls sensitivity and resistance to [Beta]-amyloid-induced cognitive and electrophysiological impairments

Publisher

Washington: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (12), p.3347

Language

English

Formats

Publication information

Publisher

Washington: National Academy of Sciences

More information

Scope and Contents

Contents

Elevated levels of the β-amyloid peptide (Aβ) are thought to contribute to cognitive and behavioral impairments observed in Alzheimer's disease (AD). Protein phosphatase 2A (PP2A) participates in multiple molecular pathways implicated in AD, and its expression and activity are reduced in postmortem brains of AD patients. PP2A is regulated by protei...

Alternative Titles

Full title

PP2A methylation controls sensitivity and resistance to [Beta]-amyloid-induced cognitive and electrophysiological impairments

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1780547567

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1780547567

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

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