Chronic treatment with tetrahydrobiopterin reverses endothelial dysfunction and oxidative stress in...
Chronic treatment with tetrahydrobiopterin reverses endothelial dysfunction and oxidative stress in hypercholesterolaemia
About this item
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Author / Creator
Cosentino, F , Hürlimann, D , Delli Gatti, C , Chenevard, R , Blau, N , Alp, N J , Channon, K M , Eto, M , Lerch, P , Enseleit, F , Ruschitzka, F , Volpe, M , Lüscher, T F and Noll, G
Publisher
London: BMJ Publishing Group Ltd and British Cardiovascular Society
Journal title
Language
English
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Publication information
Publisher
London: BMJ Publishing Group Ltd and British Cardiovascular Society
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More information
Scope and Contents
Contents
Background:Reduced availability of tetrahydrobiopterin (BH4), an essential cofactor of nitric oxide (NO) synthase (NOS), decreases NO production and increases reactive oxygen species. Both mechanisms contribute to atherosclerotic vascular disease. Although acute supplementation of BH4 improves endothelial dysfunction, the effect of chronic BH4 in h...
Alternative Titles
Full title
Chronic treatment with tetrahydrobiopterin reverses endothelial dysfunction and oxidative stress in hypercholesterolaemia
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Record Identifier
TN_cdi_proquest_journals_1780693373
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1780693373
Other Identifiers
ISSN
1355-6037
E-ISSN
1468-201X
DOI
10.1136/hrt.2007.122184
