Association of a polymorphism of the transforming growth factor- 1 gene with cerebral amyloid angiop...
Association of a polymorphism of the transforming growth factor- 1 gene with cerebral amyloid angiopathy
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London: BMJ Publishing Group LTD
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English
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London: BMJ Publishing Group LTD
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Background: A recent study showed that transforming growth factor-β1 (TGF-β1) induces amyloid-β deposition in cerebral blood vessels and meninges of a transgenic mouse model of Alzheimer's disease (AD), and that TGF-β1 mRNA levels are correlated with cerebral amyloid angiopathy (CAA) in human AD brains. A T/C polymorphism at codon 10 in exon 1 of t...
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Full title
Association of a polymorphism of the transforming growth factor- 1 gene with cerebral amyloid angiopathy
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TN_cdi_proquest_journals_1781239006
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1781239006
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ISSN
0022-3050
E-ISSN
1468-330X
DOI
10.1136/jnnp.2003.034454
