Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis
Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis
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Korfei, Martina , Skwarna, Sylwia , Henneke, Ingrid , MacKenzie, BreAnne , Klymenko, Oleksiy , Saito, Shigeki , Ruppert, Clemens , von der Beck, Daniel , Mahavadi, Poornima , Klepetko, Walter , Bellusci, Saverio , Crestani, Bruno , Pullamsetti, Soni Savai , Fink, Ludger , Seeger, Werner , Krämer, Oliver Holger and Guenther, Andreas
Publisher
England: BMJ Publishing Group LTD
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English
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England: BMJ Publishing Group LTD
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BackgroundActivation and differentiation of fibroblasts into contractile protein-expressing myofibroblasts and their acquired apoptosis-resistant phenotype are critical factors towards the development of idiopathic pulmonary fibrosis (IPF), a fatal disease characterised by distorted pulmonary structure and excessive extracellular matrix (ECM) depos...
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Full title
Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis
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TN_cdi_proquest_journals_1781826073
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1781826073
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ISSN
0040-6376
E-ISSN
1468-3296
DOI
10.1136/thoraxjnl-2014-206411