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A phase II, open-label trial of bortezomib (VELCADE®) in combination with gemcitabine and cisplatin...

A phase II, open-label trial of bortezomib (VELCADE®) in combination with gemcitabine and cisplatin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1784028316

A phase II, open-label trial of bortezomib (VELCADE®) in combination with gemcitabine and cisplatin in patients with locally advanced or metastatic non-small cell lung cancer

About this item

Full title

A phase II, open-label trial of bortezomib (VELCADE®) in combination with gemcitabine and cisplatin in patients with locally advanced or metastatic non-small cell lung cancer

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer chemotherapy and pharmacology, 2016-05, Vol.77 (5), p.949-956

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Background
Bortezomib is a selective reversible proteasome inhibitor with proapoptotic effects. Preclinical and phase I clinical data suggest activity of bortezomib in NSCLC, either as monotherapy or in combination with chemotherapeutic agents including gemcitabine and cisplatin.
Methods
Chemotherapy-naïve patients with inoperable stage II...

Alternative Titles

Full title

A phase II, open-label trial of bortezomib (VELCADE®) in combination with gemcitabine and cisplatin in patients with locally advanced or metastatic non-small cell lung cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1784028316

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1784028316

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-016-2997-7

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