c-Rel is a critical mediator of NF-[kappa]B-dependent TRAIL resistance of pancreatic cancer cells
c-Rel is a critical mediator of NF-[kappa]B-dependent TRAIL resistance of pancreatic cancer cells
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Author / Creator
Geismann, C , Grohmann, F , Sebens, S , Wirths, G , Dreher, A , Häsler, R , Rosenstiel, P , Hauser, C , Egberts, J-h , Trauzold, A , Schneider, G , Sipos, B , Zeissig, S , Schreiber, S , Schäfer, H and Arlt, A
Publisher
London: Springer Nature B.V
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English
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Publisher
London: Springer Nature B.V
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Contents
Pancreatic ductal adenocarcinoma (PDAC) represents one of the deadliest malignancies with an overall life expectancy of 6 months despite current therapies. NF-κB signalling has been shown to be critical for this profound cell-autonomous resistance against chemotherapeutic drugs and death receptor-induced apoptosis, but little is known about the rol...
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Full title
c-Rel is a critical mediator of NF-[kappa]B-dependent TRAIL resistance of pancreatic cancer cells
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TN_cdi_proquest_journals_1786232477
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1786232477
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E-ISSN
2041-4889
DOI
10.1038/cddis.2014.417
