941. Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Transgenic Effects on Irradiation-In...
941. Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Transgenic Effects on Irradiation-Induced Reactive Oxygen Species (ROS) in Normal Tissue Also Destabilize Antioxidant Pools in Orthotopic Oral Cavity Tumors
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Milwaukee: Elsevier Limited
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English
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Milwaukee: Elsevier Limited
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Overexpression of MnSOD has been demonstrated to sensitize tumor cells to irradiation. To determine the mechanism, we injected SCC-VII murine squamous cell carcinoma cells into the cheeks of C3H/HeNsd mice. Seven days later, the mice were injected eitherintravenously (I.V.) or intraorally (I.O.) with MnSOD-PL (100 μg plasmid DNA). Twenty-four hours...
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Full title
941. Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Transgenic Effects on Irradiation-Induced Reactive Oxygen Species (ROS) in Normal Tissue Also Destabilize Antioxidant Pools in Orthotopic Oral Cavity Tumors
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TN_cdi_proquest_journals_1792792611
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1792792611
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ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1016/j.ymthe.2006.08.1032