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941. Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Transgenic Effects on Irradiation-In...

941. Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Transgenic Effects on Irradiation-In...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1792792611

941. Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Transgenic Effects on Irradiation-Induced Reactive Oxygen Species (ROS) in Normal Tissue Also Destabilize Antioxidant Pools in Orthotopic Oral Cavity Tumors

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Full title

941. Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Transgenic Effects on Irradiation-Induced Reactive Oxygen Species (ROS) in Normal Tissue Also Destabilize Antioxidant Pools in Orthotopic Oral Cavity Tumors

Publisher

Milwaukee: Elsevier Limited

Journal title

Molecular therapy, 2006-05, Vol.13 (S1), p.S363

Language

English

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Publication information

Publisher

Milwaukee: Elsevier Limited

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Scope and Contents

Contents

Overexpression of MnSOD has been demonstrated to sensitize tumor cells to irradiation. To determine the mechanism, we injected SCC-VII murine squamous cell carcinoma cells into the cheeks of C3H/HeNsd mice. Seven days later, the mice were injected eitherintravenously (I.V.) or intraorally (I.O.) with MnSOD-PL (100 μg plasmid DNA). Twenty-four hours...

Alternative Titles

Full title

941. Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Transgenic Effects on Irradiation-Induced Reactive Oxygen Species (ROS) in Normal Tissue Also Destabilize Antioxidant Pools in Orthotopic Oral Cavity Tumors

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Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1792792611

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1792792611

Other Identifiers

ISSN

1525-0016

E-ISSN

1525-0024

DOI

10.1016/j.ymthe.2006.08.1032

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