947. Gene Directed Enzyme/Prodrug Therapy of Human Glioma Xenografts Using Mutant Escherichia coli C...
947. Gene Directed Enzyme/Prodrug Therapy of Human Glioma Xenografts Using Mutant Escherichia coli Cytosine Deaminase
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Publisher
Milwaukee: Elsevier Limited
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Language
English
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Publisher
Milwaukee: Elsevier Limited
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Contents
Combined treatment using suicide gene therapy and radiation therapy has the potential to become a powerful new method of cancer therapy. We have developed a non-replicative adenoviral vector encoding a mutant bacterial cytosine deaminase (bCD) gene harboring substitution of an alanine (A) for the aspartic acid (D) at position 314 in the CD protein...
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Full title
947. Gene Directed Enzyme/Prodrug Therapy of Human Glioma Xenografts Using Mutant Escherichia coli Cytosine Deaminase
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TN_cdi_proquest_journals_1792799237
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1792799237
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ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1016/j.ymthe.2006.08.1038
