Phase I Trial of Sequential Administration of Recombinant DNA and Adenovirus Expressing L523S Protei...
Phase I Trial of Sequential Administration of Recombinant DNA and Adenovirus Expressing L523S Protein in Early Stage Non-Small-Cell Lung Cancer
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Full title
Author / Creator
Nemunaitis, John , Meyers, Thomas , Senzer, Neil , Cunningham, Casey , West, Howard , Vallieres, Eric , Anthony, Stephen , Vukelja, Svetislava , Berman, Barry , Tully, Heather , Pappen, Beena , Sarmiento, Stephen , Arzaga, Rosemarie , Duniho, Steven , Engardt, Susan , Meagher, Madeleine and Cheever, Martin A.
Publisher
United States: Elsevier Limited
Journal title
Language
English
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Publication information
Publisher
United States: Elsevier Limited
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Scope and Contents
Contents
L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S) and when delivered following incorporation into an E1B-deleted adenovirus (Ad/L523S). We performed a phase I clinical trial in 13 stage IB, IIA, and IIB non-small-cell lung cancer patie...
Alternative Titles
Full title
Phase I Trial of Sequential Administration of Recombinant DNA and Adenovirus Expressing L523S Protein in Early Stage Non-Small-Cell Lung Cancer
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_1792806051
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1792806051
Other Identifiers
ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1016/j.ymthe.2006.01.013
