RNA Interference in Vitro and in Vivo Using a Chitosan/siRNA Nanoparticle System
RNA Interference in Vitro and in Vivo Using a Chitosan/siRNA Nanoparticle System
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Publisher
Milwaukee: Elsevier Limited
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Language
English
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Publisher
Milwaukee: Elsevier Limited
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Contents
This work introduces a novel chitosan-based siRNA nanoparticle delivery system for RNA interference in vitro and in vivo. The formation of interpolyelectrolyte complexes between siRNA duplexes (21-mers) and chitosan polymer into nanoparticles, ranging from 40 to 600 nm, was shown using atomic force microscopy and photon correlation spectroscopy. Ra...
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Full title
RNA Interference in Vitro and in Vivo Using a Chitosan/siRNA Nanoparticle System
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TN_cdi_proquest_journals_1792808759
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1792808759
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ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1016/j.ymthe.2006.04.010
