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Improved system for helper-dependent adenoviral vector production

Improved system for helper-dependent adenoviral vector production

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1792822428

Improved system for helper-dependent adenoviral vector production

About this item

Full title

Improved system for helper-dependent adenoviral vector production

Author / Creator

Publisher

United States: Elsevier Inc

Journal title

Molecular therapy, 2003-11, Vol.8 (5), p.846-852

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Helper-dependent adenoviral vectors (HDAds) are devoid of all viral coding sequences and have demonstrated tremendous potential for gene therapy by providing increased cloning capacity (up to 37 kb) and long-term, high-level transgene expression in vivo with negligible toxicity. Currently, the most widely used method of producing HDAds is the Cre/l...

Alternative Titles

Full title

Improved system for helper-dependent adenoviral vector production

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1792822428

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1792822428

Other Identifiers

ISSN

1525-0016

E-ISSN

1525-0024

DOI

10.1016/j.ymthe.2003.08.014

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